Cambridge Healthtech Institute’s 6th Annual

Adoptive Cell Therapy – ACT 2

Engineering the Second Generation of CAR Ts, TCRs, and TILs

Part of The Immuno-Oncology Summit

August 5-6, 2019

Efforts to engineer CAR Ts, NKs, TCRs, and TILs with greater precision, safety profiles, and efficacy are leading to the second generation of improved adoptive cell therapies (ACT 2). With multiple engineered receptors already making preclinical impact, many biotech and pharma companies are preparing for the next wave of clinical trials. The end goal is still the same: improved patient outcomes. However, there remain technical considerations and translational challenges relating to cell therapy development, manufacturing practicability, clinical trial approaches, cell quality and persistence, and patient management. Cambridge Healthtech Institute’s Sixth Annual Adoptive Cell Therapy conference focuses on the next steps needed to deliver CAR, TCR, and TIL into the clinic.   


Cover will include, but is not limited to:


Progress in:

  • Chimeric antigen receptors (CAR) including gene edited CAR Ts
  • Tandem CARs
  • T cell receptors (TCRs)
  • Tumor infiltrating lymphocytes (TILs)
  • Cytotoxic T lymphocytes (CTLs)
  • Next-generation CAR Ts
  • NK cells
  • T Regs

Impact of:

  • Genome editing (CRISPR/Cas 9, TAL)
  • Gating strategies
  • Antigen presentation
  • New approaches to activation and engagement
  • Kill switches

Potential of:

  • Off-the-shelf therapies
  • Targeting solid tumors
  • Manipulating the tumor microenvironment
  • Combination therapies
  • New antigens

Solutions for:

  • Translation
  • Scale-up
  • Manufacturing


If you would like to submit a proposal to give a presentation at this meeting, please click here.


The deadline for priority consideration is January 11, 2019.


All proposals are subject to review by session chairmen and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


For more details on the conference, please contact:
Mary Ann Brown

Executive Director, Conferences

Cambridge Healthtech Institute

Phone: (+1) 781-972-5497


For partnering and sponsorship information, please contact:

Rod Eymael

Manager, Business Development

Cambridge Healthtech Institute

Phone: (+1) 781-247-6286




Connect With Us


For meeting questions or suggestions, please contact:

Julia Boguslavsky
Executive Director, Conferences
Cambridge Healthtech Institute


For partnering and sponsorship info, please contact:

Rod Eymael
Manager, Business Development
Cambridge Healthtech Institute
+1 781.247.6286


For media and association partnerships, please contact:

Pete DeOlympio
Sr. Marketing Manager
Cambridge Healthtech Institute
+1 781.972.5415