Cambridge Healthtech Institute’s Inaugural

Emerging Techniques in Synthetic Biology

Customizing Immune Cells for More Effective Immunotherapies
August 31 - September 1, 2017 | Sheraton Boston | Boston, MA

Cell-based immunotherapies provide a unique opportunity to incorporate synthetic biology approaches to create safer, more effective cancer therapies. However, despite numerous advances, the field has not reached the point where genetic parts can be predictably combined to achieve a desired outcome. At Cambridge Healthtech Institute’s Inaugural Techniques in Synthetic Biology event, industry visionaries will review the development of synthetic receptors, switches, and circuits to control the location, duration, and strength of T cell activity against tumors. Cellular engineering and genome editing of host cells to improve the efficacy of cell-based cancer therapeutics will also be addressed. Overall, this event will build a solid foundation for a robust and impactful synthetic biology toolbox.

Preliminary Agenda


Synthetic Biology in Cellular Immunotherapy

Wilson Wong, Ph.D., Assistant Professor, Biomedical Engineering, Boston University

Engineering Smarter and Stronger T Cells for Cancer Immunotherapy

Yvonne Y. Chen, Ph.D., Assistant Professor, Chemical and Biomolecular Engineering, University of California, Los Angeles


Reining in T Cell Therapaies in Two Dimensions Should Promote Both Safety and Efficacy

David M. Spencer, Ph.D., CSO, Bellicum Therapeutics


Emerging Investigator: Hacking Immune Cells with Synthetic Notch Receptors to Expand Their Therapeutic Potential

Kole T. Roybal, Ph.D., Assistant Professor, Microbiology, Immunology, University of California, San Francisco

Phospho Neoantigens: Approaches to Neoantigen Prediction

Mark Cobbold, MRCP, Ph.D., Associate Professor, Massachusetts General Hospital Cancer Center

Synthetic Morphogenesis: Objectives, Current Approaches, Future Potential

Ron Weiss, Professor, Biological Engineering, Massachusetts Institute of Technology

Emerging Investigator: Synthetic Biology Approaches for Engineering Platelets as Delivery Systems

Tara L. Deans, Ph.D., Assistant Professor, Department of Bioengineering, University of Utah

A Modular Approach to Engineering a Tumor-Specific Oncolytic Adenovirus with Small Molecule-Controlled Expanded Tropism

Shigeki Miyake-Stoner, Ph.D., Translational Specialist, Molecular and Cell Biology Laboratories, Salk Institute for Biological Studies

For more details on the conference, please contact:
Samantha Drinkwater
Senior Conference Director
Cambridge Healthtech Institute

For exhibit & sponsorship opportunities, please contact: 
Rod Eymael
Manager, Business Development

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